St. Agnes of Montepulciano was born to a wealthy family in Italy in 1268. She was a pious child and knew she wanted to join a convent by age 6. She entered the convent in Montepulciano when she was 9 years old. She later went to Procena when her spiritual director was appointed abbess there. When St. Agnes was 15 years old, she received special permission from Pope Nicholas IV to become an abbess. She later returned to Montepulciano to work in a new Dominican convent, and she was the prioress there for the last 17 years of her life. St. Agnes died April 20, 1317. People reported miracles at her tomb, and her body was found incorrupt.